Research status and challenges of HBV cccDNA

Current antiviral treatment regimens seldom clear hepatitis B virus (HBV) infection and achieve complete cure, and therefore, many patients need long-term or even life-long antiviral therapy with nucleos(t)ide analogues. The root cause is the presence of covalently closed circular DNA (cccDNA) with...

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Bibliographic Details
Main Author: ZHANG Jiming
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2019-06-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=9949