Loss of MyoD and Myf5 in Skeletal Muscle Stem Cells Results in Altered Myogenic Programming and Failed Regeneration

Summary: MyoD and Myf5 are fundamental regulators of skeletal muscle lineage determination in the embryo, and their expression is induced in satellite cells following muscle injury. MyoD and Myf5 are also expressed by satellite cell precursors developmentally, although the relative contribution of h...

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Bibliographic Details
Main Authors: Masakazu Yamamoto, Nicholas P. Legendre, Arpita A. Biswas, Alexander Lawton, Shoko Yamamoto, Shahragim Tajbakhsh, Gabrielle Kardon, David J. Goldhamer
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118300535