Tissue Clearing and Light Sheet Microscopy: Imaging the Unsectioned Adult Zebra Finch Brain at Cellular Resolution

The inherent complexity of brain tissue, with brain cells intertwining locally and projecting to distant regions, has made three-dimensional visualization of intact brains a highly desirable but challenging task in neuroscience. The natural opaqueness of tissue has traditionally limited researchers...

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Bibliographic Details
Main Authors: Mariana Diales Rocha, Daniel Normen Düring, Philipp Bethge, Fabian F. Voigt, Staffan Hildebrand, Fritjof Helmchen, Alexander Pfeifer, Richard Hans Robert Hahnloser, Manfred Gahr
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Neuroanatomy
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnana.2019.00013/full