Role of ARF6, Rab11 and external Hsp90 in the trafficking and recycling of recombinant-soluble Neisseria meningitidis adhesin A (rNadA) in human epithelial cells.

Neisseria meningitidis adhesin A (NadA) is a meningococcus surface protein thought to assist in the adhesion of the bacterium to host cells. We have previously shown that NadA also promotes bacterial internalization in a heterologous expression system. Here we have used the soluble recombinant NadA...

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Main Authors: Giuseppe Bozza, Mirco Capitani, Paolo Montanari, Barbara Benucci, Marco Biancucci, Vincenzo Nardi-Dei, Elena Caproni, Riccardo Barrile, Benedetta Picciani, Silvana Savino, Beatrice Aricò, Rino Rappuoli, Mariagrazia Pizza, Alberto Luini, Michele Sallese, Marcello Merola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4210143?pdf=render