Pro-Arrhythmic Ventricular Remodeling Is Associated With Increased Respiratory and Low-Frequency Oscillations of Monophasic Action Potential Duration in the Chronic Atrioventricular Block Dog Model

Pro-Arrhythmic Ventricular Remodeling Is Associated With Increased Respiratory and Low-Frequency Oscillations of Monophasic Action Potential Duration in the Chronic Atrioventricular Block Dog Model

In addition to beat-to-beat fluctuations, action potential duration (APD) oscillates at (1) a respiratory frequency and (2) a low frequency (LF) (<0.1 Hz), probably caused by bursts of sympathetic nervous system discharge. This study investigates whether ventricular remodeling in the chronic...

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Bibliographic Details
Main Authors: David Jaap Sprenkeler, Jet D. M. Beekman, Alexandre Bossu, Albert Dunnink, Marc A. Vos
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Physiology
Subjects:
chronic AV block dog
electrical remodeling
respiration
action potential duration
low-frequency oscillations
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01095/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01095/full

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