Randomised prospective phase II trial in multiple brain metastases comparing outcomes between hippocampal avoidance whole brain radiotherapy with or without simultaneous integrated boost: HA-SIB-WBRT study protocol

Randomised prospective phase II trial in multiple brain metastases comparing outcomes between hippocampal avoidance whole brain radiotherapy with or without simultaneous integrated boost: HA-SIB-WBRT study protocol

Abstract Background Recent evidence supports hippocampal avoidance with whole brain radiotherapy (HA-WBRT) as the recommended treatment option in patients with good prognosis and multiple brain metastases as this results in better neurocognitive preservation compared to whole brain radiotherapy. How...

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Bibliographic Details
Main Authors: Brendan Seng Hup Chia, Jing Yun Leong, Ashley Li Kuan Ong, Cindy Lim, Shi Hui Poon, Melvin Lee Kiang Chua, Kevin Lee Min Chua, Grace Kusumawidjaja, Eu Tiong Chua, Fuh Yong Wong, Tih Shih Lee
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Cancer
Subjects:
Whole brain radiotherapy
Hippocampal-avoidance whole brain radiotherapy
Brain metastases
Study protocol
Online Access:http://link.springer.com/article/10.1186/s12885-020-07565-y

Internet

http://link.springer.com/article/10.1186/s12885-020-07565-y

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