Interdependence theory of tissue failure: bulk and boundary effects

The mortality rate of many complex multicellular organisms increases with age, which suggests that net ageing damage is accumulative, despite remodelling processes. But how exactly do these little mishaps in the cellular level accumulate and spread to become a systemic catastrophe? To address this q...

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Bibliographic Details
Main Authors: Daniel Suma, Aylin Acun, Pinar Zorlutuna, Dervis Can Vural
Format: Article
Language:English
Published: The Royal Society 2018-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.171395