Epigallocatechin-3-Gallate (EGCG) Suppresses Pancreatic Cancer Cell Growth, Invasion, and Migration partly through the Inhibition of Akt Pathway and Epithelial–Mesenchymal Transition: Enhanced Efficacy When Combined with Gemcitabine

Most pancreatic cancers are usually diagnosed at an advanced stage when they have already metastasized. Epigallocatechin-3-gallate (EGCG), a major polyphenolic constituent of green tea, has been shown to reduce pancreatic cancer growth, but its effect on metastasis remains elusive. This study evalua...

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Bibliographic Details
Main Authors: Ran Wei, Natalia E. Cortez Penso, Robert M. Hackman, Yuefei Wang, Gerardo G. Mackenzie
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Nutrients
Subjects:
Akt
EMT
Online Access:https://www.mdpi.com/2072-6643/11/8/1856