Inhibition of Mitochondrial Division Attenuates Cisplatin-Induced Toxicity in the Neuromast Hair Cells

Cisplatin and other related platinum antineoplastic drugs are commonly used in the treatment of a variety of cancers in both adults and children but are often associated with severe side effects, including hearing loss. Cisplatin’s ototoxic effects are multifaceted, culminating in irreversible damag...

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Bibliographic Details
Main Authors: Jonathon W. Vargo, Steven N. Walker, Suhasini R. Gopal, Aditi R. Deshmukh, Brian M. McDermott Jr., Kumar N. Alagramam, Ruben Stepanyan
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00393/full