Microglia-Mediated Neuroinflammation and Neurotrophic Factor-Induced Protection in the MPTP Mouse Model of Parkinson’s Disease-Lessons from Transgenic Mice

Microglia-Mediated Neuroinflammation and Neurotrophic Factor-Induced Protection in the MPTP Mouse Model of Parkinson’s Disease-Lessons from Transgenic Mice

Parkinson’s disease (PD) is a neurodegenerative disease characterised by histopathological and biochemical manifestations such as loss of midbrain dopaminergic (DA) neurons and decrease in dopamine levels accompanied by a concomitant neuroinflammatory response in the affected brain regions. Over the...

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Bibliographic Details
Main Authors: Venissa Machado, Tanja Zöller, Abdelraheim Attaai, Björn Spittau
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:International Journal of Molecular Sciences
Subjects:
MPTP
neuroinflammation
microglia
Parkinson’s disease
neurotrophic factors
neuroprotection
Online Access:http://www.mdpi.com/1422-0067/17/2/151

Internet

http://www.mdpi.com/1422-0067/17/2/151

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