The Food Contaminants Pyrrolizidine Alkaloids Disturb Bile Acid Homeostasis Structure-Dependently in the Human Hepatoma Cell Line HepaRG

Pyrrolizidine alkaloids (PAs) are a group of secondary plant metabolites being contained in various plant species. The consumption of contaminated food can lead to acute intoxications in humans and exert severe hepatotoxicity. The development of jaundice and elevated bile acid concentrations in bloo...

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Bibliographic Details
Main Authors: Josephin Glück, Marcus Henricsson, Albert Braeuning, Stefanie Hessel-Pras
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/10/5/1114