Diffusion MRI quantifies early axonal loss in the presence of nerve swelling

Abstract Background Magnetic resonance imaging markers have been widely used to detect and quantify white matter pathologies in multiple sclerosis. We have recently developed a diffusion basis spectrum imaging (DBSI) to distinguish and quantify co-existing axonal injury, demyelination, and inflammat...

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Bibliographic Details
Main Authors: Tsen-Hsuan Lin, Chia-Wen Chiang, Carlos J. Perez-Torres, Peng Sun, Michael Wallendorf, Robert E. Schmidt, Anne H. Cross, Sheng-Kwei Song
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12974-017-0852-3