THE ROLES OF LIPIDS AND NUCLEIC ACIDS IN HIV-1 ASSEMBLY

During HIV-1 assembly, precursor Gag (PrGag) proteins are delivered to plasma membrane (PM) assembly sites, where they are triggered to oligomerize and bud from cells as immature virus particles. The delivery and triggering processes are coordinated by the PrGag matrix (MA) and nucleocapsid (NC) dom...

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Bibliographic Details
Main Authors: Ayna eAlfadhli, Eric eBarklis
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Microbiology
Subjects:
RNA
Gag
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00253/full