A quantitative proteomic analysis uncovers the relevance of CUL3 in bladder cancer aggressiveness.

To identify aggressiveness-associated molecular mechanisms and biomarker candidates in bladder cancer, we performed a SILAC (Stable Isotope Labelling by Amino acids in Cell culture) proteomic analysis comparing an invasive T24 and an aggressive metastatic derived T24T bladder cancer cell line. A tot...

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Bibliographic Details
Main Authors: Laura Grau, Jose L Luque-Garcia, Pilar González-Peramato, Dan Theodorescu, Joan Palou, Jesus M Fernandez-Gomez, Marta Sánchez-Carbayo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3540081?pdf=render