Molecular Mechanisms of p63-Mediated Squamous Cancer Pathogenesis

Molecular Mechanisms of p63-Mediated Squamous Cancer Pathogenesis

The <i>p63</i> gene is a member of the p53/p63/p73 family of transcription factors and plays a critical role in development and homeostasis of squamous epithelium. <i>p63</i> is transcribed as multiple isoforms; &#916;Np63&#945;, the predominant p63 isoform in stratif...

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Bibliographic Details
Main Authors: Michael A. Moses, Andrea L. George, Nozomi Sakakibara, Kanwal Mahmood, Roshini M. Ponnamperuma, Kathryn E. King, Wendy C. Weinberg
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
p63
p53 family
keratinocytes
squamous carcinogenesis
epidermal homeostasis
epidermal morphogenesis
Online Access:https://www.mdpi.com/1422-0067/20/14/3590

Internet

https://www.mdpi.com/1422-0067/20/14/3590

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