The landscape of bispecific T cell engager in cancer treatment

Abstract T cell-based immunotherapies have revolutionized treatment paradigms in various cancers, however, limited response rates secondary to lack of significant T-cell infiltration in the tumor site remain a major problem. To address this limitation, strategies for redirecting T cells to treat can...

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Bibliographic Details
Main Authors: Shujie Zhou, Mingguo Liu, Fei Ren, Xiangjiao Meng, Jinming Yu
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Biomarker Research
Subjects:
Online Access:https://doi.org/10.1186/s40364-021-00294-9