PGC-1α Protects against Hepatic Ischemia Reperfusion Injury by Activating PPARα and PPARγ and Regulating ROS Production

PGC-1α Protects against Hepatic Ischemia Reperfusion Injury by Activating PPARα and PPARγ and Regulating ROS Production

Peroxisome proliferator-activated receptors (PPARs) α and γ have been shown to be protective in hepatic ischemia/reperfusion (I/R) injury. However, the precise role of PPARγ coactivator-1α (PGC-1α), which can coactivate both of these receptors, in hepatic I/R injury, remains largely unknown. This st...

Full description

Bibliographic Details
Main Authors: Chaoqun Wang, Zihao Li, Baolei Zhao, Yaohua Wu, Yao Fu, Kai Kang, Yao Li, Liqian Dong, Xiaozhuang Li, Bao Zhang, Huibo Wu, Benqiang Shen, Yanan Xu, Shangha Pan, Hongchi Jiang, Dawei Wang, Yong Ma
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/6677955

Internet

http://dx.doi.org/10.1155/2021/6677955

Similar Items