Monitoring Apoptosis of Breast Cancer Xenograft After Paclitaxel Treatment With Tc-Labeled Duramycin SPECT/CT

Our goal was to validate the feasibility of 99m Tc-duramycin as a potential apoptosis probe for monitoring tumor response to paclitaxel in breast cancer xenografts. The binding of 99m Tc-duramycin to phosphatidylethanolamine was validated in vitro using paclitaxel-treated human breast carcinoma MDA-...

Full description

Bibliographic Details
Main Authors: Rui Luo, Lei Niu, Fan Qiu, Wei Fang, Tong Fu, Ming Zhao, Ying-Jian Zhang, Zi-Chun Hua, Xiao-Feng Li, Feng Wang
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2016-01-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1177/1536012115624918