Extreme evolutionary disparities seen in positive selection across seven complex diseases.

Positive selection is known to occur when the environment that an organism inhabits is suddenly altered, as is the case across recent human history. Genome-wide association studies (GWASs) have successfully illuminated disease-associated variation. However, whether human evolution is heading towards...

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Bibliographic Details
Main Authors: Erik Corona, Joel T Dudley, Atul J Butte
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2923198?pdf=render