A Novel OGR1 (GPR68) Inhibitor Attenuates Inflammation in Murine Models of Colitis

A Novel OGR1 (GPR68) Inhibitor Attenuates Inflammation in Murine Models of Colitis

Background and Aims: Local extracellular acidification is associated with several conditions, such as ischemia, cancer, metabolic disease, respiratory diseases, and inflammatory bowel disease (IBD). Several recent studies reported a link between IBD and a family of pH-sensing G protein-coupled recep...

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Bibliographic Details
Main Authors: Cheryl de Vallière, Katharina Bäbler, Philipp Busenhart, Marlene Schwarzfischer, Chiaki Maeyashiki, Cordelia Schuler, Kirstin Atrott, Silvia Lang, Marianne R. Spalinger, Michael Scharl, Pedro A. Ruiz-Castro, Martin Hausmann, Gerhard Rogler
Format: Article
Language:English
Published: Karger Publishers 2021-07-01
Series:Inflammatory Intestinal Diseases
Subjects:
ovarian cancer g protein-coupled receptor 1 antagonist
ph-sensing g protein-coupled receptor
inflammatory bowel disease
Online Access:https://www.karger.com/Article/FullText/517474

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https://www.karger.com/Article/FullText/517474

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