The frequency-response electroretinogram distinguishes cone and abnormal rod function in rd12 mice.

Early studies on Rpe65 knockout mice reported that remaining visual function was attributable to cone function. However, this finding has been challenged more and more as time has passed. Electroretinograms (ERGs) showed that rd12 mice, a spontaneous animal model of RPE65 Leber's congenital ama...

Full description

Bibliographic Details
Main Authors: Xufeng Dai, Hua Zhang, Ying He, Yan Qi, Bo Chang, Ji-jing Pang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4338143?pdf=render