Emerging Roles of Tripartite Motif-Containing Family Proteins (TRIMs) in Eliminating Misfolded Proteins

Emerging Roles of Tripartite Motif-Containing Family Proteins (TRIMs) in Eliminating Misfolded Proteins

Protein quality control (PQC) is pivotal for eukaryotic cells to eliminate misfolded proteins and maintain cellular homeostasis. A decreased or increased capacity of PQC is associated with various diseases, e.g., neurodegenerative diseases and cancers. Recently, increasing evidences have suggested t...

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Bibliographic Details
Main Authors: Litian Zhang, Lukman O. Afolabi, Xiaochun Wan, Yang Li, Liang Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
TRIMs
misfolded proteins
aggregates
degradation
UPS
autophagy
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00802/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00802/full

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