mRNA decay proteins are targeted to poly(A)+ RNA and dsRNA-containing cytoplasmic foci that resemble P-bodies in Entamoeba histolytica.

In higher eukaryotes, mRNA degradation and RNA-based gene silencing occur in cytoplasmic foci referred to as processing bodies (P-bodies). In protozoan parasites, the presence of P-bodies and their putative role in mRNA decay have yet to be comprehensively addressed. Identification of P-bodies might...

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Main Authors: Itzel López-Rosas, Esther Orozco, Laurence A Marchat, Guillermina García-Rivera, Nancy Guillen, Christian Weber, Eduardo Carrillo-Tapia, Olga Hernández de la Cruz, Carlos Pérez-Plasencia, César López-Camarillo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3454373?pdf=render