The genetic component of preeclampsia: A whole-exome sequencing study.

Preeclampsia is a major cause of maternal and perinatal deaths. The aetiology of preeclampsia is largely unknown but a polygenetic component is assumed. To explore this hypothesis, we performed an in-depth whole-exome sequencing study in women with (cases, N = 50) and without (controls, N = 50) pree...

Full description

Bibliographic Details
Main Authors: Anette Tarp Hansen, Jens Magnus Bernth Jensen, Anne-Mette Hvas, Mette Christiansen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5951572?pdf=render