Interleukin-1β Alters Hebbian Synaptic Plasticity in Multiple Sclerosis

Interleukin-1β Alters Hebbian Synaptic Plasticity in Multiple Sclerosis

In multiple sclerosis (MS), inflammation alters synaptic transmission and plasticity, negatively influencing the disease course. In the present study, we aimed to explore the influence of the proinflammatory cytokine IL-1β on peculiar features of associative Hebbian synaptic plasticity, such as inpu...

Full description

Bibliographic Details
Main Authors: Mario Stampanoni Bassi, Fabio Buttari, Carolina Gabri Nicoletti, Francesco Mori, Luana Gilio, Ilaria Simonelli, Nicla De Paolis, Girolama Alessandra Marfia, Roberto Furlan, Annamaria Finardi, Diego Centonze, Ennio Iezzi
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
paired associative stimulation (PAS)
multiple sclerosis (MS)
interleukin (IL)-1β
synaptic plasticity
long-term potentiation (LTP)
transcranial magnetic stimulation (TMS)
Online Access:https://www.mdpi.com/1422-0067/21/19/6982

Internet

https://www.mdpi.com/1422-0067/21/19/6982

Similar Items