Triterpenoid-enriched extract of Ilex kudingcha inhibits aggregated LDL-induced lipid deposition in macrophages by downregulating low density lipoprotein receptor-related protein 1 (LRP1)

Macrophage-derived foam cell formation is considered to be a critical step in the development of atherosclerosis. In the present study, we evaluated the inhibitory effect of Ilex kudingcha triterpenoid-enriched extract (TS) on foam cell formation in THP-1 macrophage cells induced by aggregated low d...

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Bibliographic Details
Main Authors: Jiao Zheng, Haiyan Zhou, Yunfang Zhao, Qixing Lun, Binglin Liu, Pengfei Tu
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615004028