Dissecting Nucleosome Function with a Comprehensive Histone H2A and H2B Mutant Library

Dissecting Nucleosome Function with a Comprehensive Histone H2A and H2B Mutant Library

Using a comprehensive library of histone H2A and H2B mutants, we assessed the biological function of each amino acid residue involved in various stress conditions including exposure to different DNA damage-inducing reagents, different growth temperatures, and other chemicals. H2B N- and H2A C-termin...

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Bibliographic Details
Main Authors: Shuangying Jiang, Yan Liu, Caiyue Xu, Yun Wang, Jianhui Gong, Yue Shen, Qingyu Wu, Jef D. Boeke, Junbiao Dai
Format: Article
Language:English
Published: Oxford University Press 2017-12-01
Series:G3: Genes, Genomes, Genetics
Subjects:
histone
heterochromatin gene silencing
DNA damage
post-translational modification
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.117.300252

Internet

http://g3journal.org/lookup/doi/10.1534/g3.117.300252

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