Prolonged versus intermittent β-lactam antibiotics intravenous infusion strategy in sepsis or septic shock patients: a systematic review with meta-analysis and trial sequential analysis of randomized trials

Abstract Background The prolonged β-lactam infusion strategy has emerged as the standard treatment for sepsis or septic shock despite its unknown efficacy. This study aimed to assess the efficacy of prolonged versus intermittent β-lactam antibiotics infusion on outcomes in sepsis or septic shock pat...

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Bibliographic Details
Main Authors: Yutaka Kondo, Kohei Ota, Haruki Imura, Naoki Hara, Nobuaki Shime
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Journal of Intensive Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40560-020-00490-z