Isoliquiritigenin suppresses human melanoma growth by targeting miR-301b/LRIG1 signaling

Isoliquiritigenin suppresses human melanoma growth by targeting miR-301b/LRIG1 signaling

Abstract Background Isoliquiritigenin (ISL), a natural flavonoid isolated from the root of licorice (Glycyrrhiza uralensis), has shown various pharmacological properties including anti-oxidant, anti-inflammatory and anti-cancer activities. MicroRNAs (miRNAs), a class of small non-coding RNAs, have b...

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Bibliographic Details
Main Authors: Shijian Xiang, Huoji Chen, Xiaojun Luo, Baichao An, Wenfeng Wu, Siwei Cao, Shifa Ruan, Zhuxian Wang, Lidong Weng, Hongxia Zhu, Qiang Liu
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Isoliquiritigenin
Melanoma
miR-301b
LRIG1
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s13046-018-0844-x

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http://link.springer.com/article/10.1186/s13046-018-0844-x

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