A Novel Iron Transporter SPD_1590 in Streptococcus pneumoniae Contributing to Bacterial Virulence Properties

A Novel Iron Transporter SPD_1590 in Streptococcus pneumoniae Contributing to Bacterial Virulence Properties

Streptococcus pneumoniae, a Gram-positive human pathogen, has evolved three main transporters for iron acquisition from the host: PiaABC, PiuABC, and PitABC. Our previous study had shown that the mRNA and protein levels of SPD_1590 are significantly upregulated in the ΔpiuA/ΔpiaA/ΔpitA triple mutant...

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Bibliographic Details
Main Authors: Xinyu Miao, Jiaojiao He, Liang Zhang, Xinlu Zhao, Ruiguang Ge, Qing-Yu He, Xuesong Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
iron transporter
S. pneumoniae
proteomics
bacterial virulence
hemin binding
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01624/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01624/full

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