Genetic, Inflammatory, and Epithelial Cell Differentiation Factors Control Expression of Human Calpain-14

Genetic, Inflammatory, and Epithelial Cell Differentiation Factors Control Expression of Human Calpain-14

Eosinophilic esophagitis (EoE) is a chronic, food-driven allergic disease resulting in eosinophilic esophageal inflammation. We recently found that EoE susceptibility is associated with genetic variants in the promoter of CAPN14, a gene with reported esophagus-specific expression. CAPN14 is dynamica...

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Bibliographic Details
Main Authors: Daniel E. Miller, Carmy Forney, Mark Rochman, Stacey Cranert, Jeffery Habel, Jeffrey Rymer, Arthur Lynch, Connor Schroeder, Josh Lee, Amber Sauder, Quinton Smith, Mehak Chawla, Michael P. Trimarchi, Xiaoming Lu, Ellen Fjellman, Michael Brusilovsky, Artem Barski, Stephen Waggoner, Matthew T. Weirauch, Marc E. Rothenberg, Leah C. Kottyan
Format: Article
Language:English
Published: Oxford University Press 2019-03-01
Series:G3: Genes, Genomes, Genetics
Subjects:
CAPN14
Eosinophilic Esophagitis
IL-13
IL-4
STAT6
Genetics of Immunity
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.118.200901

Internet

http://g3journal.org/lookup/doi/10.1534/g3.118.200901

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