Evaluating tools for live imaging of structural plasticity at the axon initial segment

The axon initial segment (AIS) is a specialised neuronal compartment involved in the maintenance of axo-dendritic polarity and in the generation of action potentials. It is also a site of significant structural plasticity – manipulations of neuronal activity in vitro and in vivo can produce changes...

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Bibliographic Details
Main Authors: Adna S Dumitrescu, Mark D Evans, Matthew S Grubb
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00268/full