'Fat's chances': Loci for phenotypic dispersion in plasma leptin in mouse models of diabetes mellitus.

BACKGROUND:Leptin, a critical mediator of feeding, metabolism and diabetes, is expressed on an incidental basis according to satiety. The genetic regulation of leptin should similarly be episodic. METHODOLOGY:Data from three mouse cohorts hosted by the Jackson Laboratory- 402 (174F, 228M) F2 Dilute...

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Bibliographic Details
Main Author: Guy M L Perry
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0222654