Stat3 mediates expression of autotaxin in breast cancer.

We determined that signal transducer and activator of transcription 3 (Stat3) is tyrosine phosphorylated in 37% of primary breast tumors and 63% of paired metastatic axillary lymph nodes. Examination of the distribution of tyrosine phosphorylated (pStat3) in primary tumors revealed heterogenous expr...

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Bibliographic Details
Main Authors: Janeen Azare, Ashley Doane, Kenneth Leslie, Qing Chang, Marjan Berishaj, Jennifer Nnoli, Kevin Mark, Hikmat Al-Ahmadie, William Gerald, Maryam Hassimi, Agnes Viale, Mary Stracke, David Lyden, Jacqueline Bromberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3225372?pdf=render