Simulation of Stimulation: Cytokine Dosage and Cell Cycle Crosstalk Driving Timing-Dependent T Cell Differentiation

Triggering an appropriate protective response against invading agents is crucial to the effectiveness of human innate and adaptive immunity. Pathogen recognition and elimination requires integration of a myriad of signals from many different immune cells. For example, T cell functioning is not quali...

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Bibliographic Details
Main Authors: Matteo Barberis, Tomáš Helikar, Paul Verbruggen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Physiology
Subjects:
CDK
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00879/full