Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker obese rats on a high salt diet

Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker obese rats on a high salt diet

Abstract Background Obesity, hypertension and prediabetes contribute greatly to coronary artery disease, heart failure and vascular events, and are the leading cause of mortality and morbidity in developed societies. Salt sensitivity exacerbates endothelial dysfunction. Herein, we investigated the e...

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Bibliographic Details
Main Authors: Vijayakumar Sukumaran, Hirotsugu Tsuchimochi, Takashi Sonobe, Mark T. Waddingham, Mikiyasu Shirai, James T. Pearson
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cardiovascular Diabetology
Subjects:
Endothelial dysfunction
Inflammation
Liraglutide
Nitric oxide
Oxidative stress
Online Access:http://link.springer.com/article/10.1186/s12933-020-01000-z

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http://link.springer.com/article/10.1186/s12933-020-01000-z

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