A systematic approach to designing statistically powerful heteroscedastic 2 × 2 factorial studies while minimizing financial costs

Abstract Background The 2 × 2 factorial design is widely used for assessing the existence of interaction and the extent of generalizability of two factors where each factor had only two levels. Accordingly, research problems associated with the main effects and interaction effects can be analyzed wi...

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Bibliographic Details
Main Authors: Show-Li Jan, Gwowen Shieh
Format: Article
Language:English
Published: BMC 2016-08-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12874-016-0214-3