A systems biology approach uncovers the core gene regulatory network governing iridophore fate choice from the neural crest.
Multipotent neural crest (NC) progenitors generate an astonishing array of derivatives, including neuronal, skeletal components and pigment cells (chromatophores), but the molecular mechanisms allowing balanced selection of each fate remain unknown. In zebrafish, melanocytes, iridophores and xanthop...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-10-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC6191144?pdf=render |