Bacterial Production, Characterization and Protein Modeling of a Novel Monofuctional Isoform of FAD Synthase in Humans: An Emergency Protein?

Bacterial Production, Characterization and Protein Modeling of a Novel Monofuctional Isoform of FAD Synthase in Humans: An Emergency Protein?

FAD synthase (FADS, EC 2.7.7.2) is the last essential enzyme involved in the pathway of biosynthesis of Flavin cofactors starting from Riboflavin (Rf). Alternative splicing of the human FLAD1 gene generates different isoforms of the enzyme FAD synthase. Besides the well characterized isoform 1 and 2...

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Bibliographic Details
Main Authors: Piero Leone, Michele Galluccio, Alberto Barbiroli, Ivano Eberini, Maria Tolomeo, Flavia Vrenna, Elisabetta Gianazza, Stefania Iametti, Francesco Bonomi, Cesare Indiveri, Maria Barile
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Molecules
Subjects:
flavin
riboflavin
flavoprotein
FAD synthase
protein modeling
over-expression
E. coli
Online Access:http://www.mdpi.com/1420-3049/23/1/116

Internet

http://www.mdpi.com/1420-3049/23/1/116

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