Perineural Invasion and Associated Pain Transmission in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the cancers with the highest incidence of perineural invasion (PNI), which often indicates a poor prognosis. Aggressive tumor cells invade nerves, causing neurogenic inflammation; the tumor microenvironment also induces nerves to undergo a series of...

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Bibliographic Details
Main Authors: Jialun Wang, Yu Chen, Xihan Li, Xiaoping Zou
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/18/4594