Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma

More than 35% of lung adenocarcinoma patients have bone metastases at diagnosis and have a poor survival. Periostin, a carboxylated matrix protein, mediates lung cancer cell dissemination by promoting epithelial-mesenchymal transition, and is involved in bone response to mechanical stress and bone f...

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Bibliographic Details
Main Authors: E Massy, JC. Rousseau, M. Gueye, E. Bonnelye, M. Brevet, L. Chambard, M. Duruisseaux, O. Borel, C. Roger, R. Guelminger, J.B. Pialat, E. Gineyts, L. Bouazza, M. Millet, JM. Maury, P. Clézardin, N. Girard, Cyrille B. Confavreux
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Journal of Bone Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221213742100018X