From Prebiotics to Probiotics: The Evolution and Functions of tRNA Modifications

All nucleic acids in cells are subject to post-transcriptional chemical modifications. These are catalyzed by a myriad of enzymes with exquisite specificity and that utilize an often-exotic array of chemical substrates. In no molecule are modifications more prevalent than in transfer RNAs. In the pr...

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Bibliographic Details
Main Authors: Katherine M. McKenney, Juan D. Alfonzo
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Life
Subjects:
Online Access:http://www.mdpi.com/2075-1729/6/1/13