Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection.

Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection.

Klebsiella pneumoniae is a significant cause of nosocomial pneumonia and an alarming pathogen owing to the recent isolation of multidrug resistant strains. Understanding of immune responses orchestrating K. pneumoniae clearance by the host is of utmost importance. Here we show that type I interferon...

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Bibliographic Details
Main Authors: Masa Ivin, Amy Dumigan, Filipe N de Vasconcelos, Florian Ebner, Martina Borroni, Anoop Kavirayani, Kornelia N Przybyszewska, Rebecca J Ingram, Stefan Lienenklaus, Ulrich Kalinke, Dagmar Stoiber, Jose A Bengoechea, Pavel Kovarik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006696

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https://doi.org/10.1371/journal.ppat.1006696

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