Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice

Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice

Individuals with Down syndrome (DS), a genetic condition caused by triplication of chromosome 21, are characterized by intellectual disability and are prone to develop Alzheimer's disease (AD), due to triplication of the amyloid precursor protein (APP) gene. Recent evidence in the Ts65Dn mouse...

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Bibliographic Details
Main Authors: Fiorenza Stagni, Andrea Giacomini, Sandra Guidi, Elisabetta Ciani, Elena Ragazzi, Mirco Filonzi, Rosaria De Iasio, Roberto Rimondini, Renata Bartesaghi
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Neurobiology of Disease
Subjects:
Down syndrome
Cognitive impairment
Pharmacotherapy
5-HT1A receptor
Alzheimer's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114003763

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http://www.sciencedirect.com/science/article/pii/S0969996114003763

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