Host reticulocytes provide metabolic reservoirs that can be exploited by malaria parasites.

Human malaria parasites proliferate in different erythroid cell types during infection. Whilst Plasmodium vivax exhibits a strong preference for immature reticulocytes, the more pathogenic P. falciparum primarily infects mature erythrocytes. In order to assess if these two cell types offer different...

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Bibliographic Details
Main Authors: Anubhav Srivastava, Darren J Creek, Krystal J Evans, David De Souza, Louis Schofield, Sylke Müller, Michael P Barrett, Malcolm J McConville, Andrew P Waters
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1004882