Chemogenetic Suppression of the Subthalamic Nucleus Induces Attentional Deficits and Impulsive Action in a Five-Choice Serial Reaction Time Task in Mice

Chemogenetic Suppression of the Subthalamic Nucleus Induces Attentional Deficits and Impulsive Action in a Five-Choice Serial Reaction Time Task in Mice

The subthalamic nucleus (STN), a key component of the basal ganglia circuitry, receives inputs from broad cerebral cortical areas and relays cortical activity to subcortical structures. Recent human and animal studies have suggested that executive function, which is assumed to consist of a set of di...

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Bibliographic Details
Main Authors: Tadaaki Nishioka, Kosuke Hamaguchi, Satoshi Yawata, Takatoshi Hikida, Dai Watanabe
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Systems Neuroscience
Subjects:
subthalamic nucleus
attention
impulsivity
5-choice serial reaction time task
DREADD
Online Access:https://www.frontiersin.org/article/10.3389/fnsys.2020.00038/full

Internet

https://www.frontiersin.org/article/10.3389/fnsys.2020.00038/full

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