CRISPR-Cas9 mediated gene deletions in lager yeast Saccharomyces pastorianus

Abstract Background The ease of use of CRISPR-Cas9 reprogramming, its high efficacy, and its multiplexing capabilities have brought this technology at the forefront of genome editing techniques. Saccharomyces pastorianus is an aneuploid interspecific hybrid of Saccharomyces cerevisiae and Saccharomy...

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Bibliographic Details
Main Authors: Arthur R. Gorter de Vries, Philip A. de Groot, Marcel van den Broek, Jean-Marc G. Daran
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-017-0835-1