Parallel and Divergent Evolutionary Solutions for the Optimization of an Engineered Central Metabolism in Methylobacterium extorquens AM1

Parallel and Divergent Evolutionary Solutions for the Optimization of an Engineered Central Metabolism in Methylobacterium extorquens AM1

Bioengineering holds great promise to provide fast and efficient biocatalysts for methanol-based biotechnology, but necessitates proven methods to optimize physiology in engineered strains. Here, we highlight experimental evolution as an effective means for optimizing an engineered Methylobacterium...

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Bibliographic Details
Main Authors: Sean Michael Carroll, Lon M. Chubiz, Deepa Agashe, Christopher J. Marx
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Microorganisms
Subjects:
Methylobacterium
bioengineering
experimental evolution
genome sequencing
RNA polymerase
C1 metabolism
Online Access:http://www.mdpi.com/2076-2607/3/2/152

Internet

http://www.mdpi.com/2076-2607/3/2/152

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