Niacin reverses migratory macrophage foam cell arrest mediated by oxLDL in vitro.

Niacin reduces vascular oxidative stress and down regulates inducible nitric oxide synthase, an enzyme mediating proatherosclerotic effects in part by increasing oxidative stress. Here, we evaluate whether Niacin reverses the redox sensitive migratory arrest of macrophages in response to oxidised(ox...

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Bibliographic Details
Main Authors: Hua Huang, Pirkko Koelle, Markus Fendler, Angelika Schroettle, Michael Czihal, Ulrich Hoffmann, Peter Jan Kuhlencordt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4270638?pdf=render