Dissecting the cellular specificity of smoking effects and reconstructing lineages in the human airway epithelium
Chronic lung diseases are characterized by molecular and cellular composition changes. Here the authors use single-cell RNA sequencing to map cell type-specific changes in human tracheal epithelium related to smoking, and to provide evidence for a tuft-like progenitor for pulmonary neuroendocrine ce...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-020-16239-z |